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US 2025/0152508 A1Published application
Salbutamol delivery compositions, devices and methods
AssigneeHoneywell International Inc.
InventorsErik Boldt, Gregory Smith
Life of this patent
Estimating the term…
Abstract
Disclosed are medicinal compositions, and devices, methods and systems which use same, comprising a carrier and at least one medicinally active compound, said carrier comprising at least 1234ze(E) and ethanol.
Claims20
A pharmaceutical composition comprising:
- a. fine particles of salbutamol;
- b. from greater than 95% by weight to less than about 98% by weight of HFO-1234ze(E);
- and
- c. from greater than 2% by weight to less than 5% by weight of ethanol.
1 more element
A pharmaceutical composition comprising:
- a. from about 2.5 mg/mL to less than about 4.5 mg/mL of fine particles salbutamol sulfate;
- b. a carrier in which said salbutamol sulfate is suspended, said carrier comprising:
- (i) from about 95% by weight to less than 99% by weight of HFO-1234ze(E);
- and (ii) from greater than 1% by weight to about 5% by weight of ethanol.
1 more element
A pharmaceutical composition in the form of an aerosol comprising:
- a. fine particles of salbutamol sulfate;
- and
- b. a carrier for said fine particulate salbutamol sulfate, said carrier comprising:
- (i) from about 94% by weight to less than 99% by weight of HFO-1234ze(E);
- (ii) from greater than 1% by weight to about 6% by weight of ethanol, wherein the amount of said salbutamol sulfate in said aerosol is from about greater than 150 micrograms to about 300 micrograms.
2 more elements
A method for delivering a prescribed dose of salbutamol sulfate comprising:
- a. providing in an MDI comprising an actuator and a pharmaceutical composition comprising:
- (1) a carrier comprising from greater than about 95% by weight to less than 99% by weight of HFO-1234ze(E);
- and (ii) from greater than 1% by weight to about 5% by weight of ethanol;
- and (2) fine particles of salbutamol sulfate;
- and
- b. actuating said MDI once to produce a single aerosol spray of said salbutamol sulfate, wherein said single spray contains the prescribed dose of said salbutamol sulfate.
3 more elements
Dependencies are inferred from the claim text.