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US 2025/0152473 A1Published application
Stable plinabulin formulations and methods of their preparation and use
AssigneeBeyondSpring Pharmaceuticals, Inc.
InventorsLan Huang, George Kenneth Lloyd, Jianmin Mao, Christopher G. Boiko, Hao Zhang
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Abstract
Described herein are plinabulin unit dose forms, kits, and methods of preparing and using plinabulin. Some embodiments relate to the use of light-protective containers, light-protective packaging, light-protected IV bags, and light-protected IV tubing.
Claims39
A vessel comprising:
- a liquid formulation comprising plinabulin, propylene glycol, and polyoxyl 15 hydroxystearates (PEG15-hydroxystearates),
- wherein the vessel is configured to block at least 85% of UV/visible light between 290 nm and 450 nm.
A kit, comprising:
- plinabulin in a light-protective container;
- and
- a light-protective packaging,
- wherein, the light-protective container blocks at least 85% of UV/visible light between 290 nm and 450 nm.
1 more element
A method of administering plinabulin to a subject in need thereof, the method comprising:
- providing plinabulin in a light-protected IV bag;
- and
- administering plinabulin to a subject in need thereof through light-protected IV tubing.
Dependencies are inferred from the claim text.