Closed loop dialysis treatment using adaptive ultrafiltration rates

A method for performing closed loop dialysis treatment for a patient, comprising:

• (a) setting an ultrafiltration pump to an ultrafiltration rate for an active duration;
• (b) measuring a total change in blood volume during the active duration;
• (c) setting the ultrafiltration pump to a minimum pump rate for a rebound duration;
• (d) measuring a rebound change in blood volume for the rebound duration;
• repeating steps (a)-(d) a first number of times to obtain a plurality of first measurements of the total change in blood volume and a plurality of second measurements of the rebound change in blood volume;
• determining a dry weight time to meet a dry weight goal for the patient based on the plurality of first measurements of the total change in blood volume and the plurality of second measurements of the rebound change in blood volume;
• and
• stopping the closed-loop dialysis treatment based on the determined dry weight time.

A dialysis system for performing closed-loop dialysis treatment, comprising:

• an ultrafiltration pump;
• a processor;
• and
• a non-transitory computer-readable storage medium having processor-executable instructions stored thereon, wherein the processor-executable instructions, when executed by the processor, facilitate:
• determining an initial ultrafiltration rate and setting the ultrafiltration pump to the determined initial ultrafiltration rate;
• measuring a total blood volume change based on the initial ultrafiltration rate;
• determining a benchmark blood volume threshold for the measured total blood volume change based on an estimated dry-weight of the patient, a currently elapsed treatment time for the closed-loop dialysis treatment, a time duration associated with the closed-loop dialysis treatment, and a start time for the closed-loop dialysis treatment;
• setting the ultrafiltration pump to a new pump rate based on comparing the determined benchmark blood volume threshold with the measured total blood volume change;
• and
• stopping the closed-loop dialysis treatment based on the estimated dry-weight of the patient.