Nucleic Acid Structure Analysis Method and Nucleic Acid Structure Analysis Device

Abstract

A nucleic acid structural analysis method includes: an HAD-MSn analysis step (101) of introducing a hydrogen radical into a space in which an ion derived from a test nucleic acid is present to perform dissociation of the ion, and performing mass spectrometry on a plurality of fragment ions generated by the dissociation to collect m/z information on the plurality of fragment ions; and a structure estimation step (103) of estimating a structure of the test nucleic acid on a basis of the m/z information on the plurality of fragment ions obtained in the HAD-MSn analysis step. This makes it possible to deal with precursor ions having various charges, and makes it easier to perform the structure estimation of the nucleic acid based on the mass spectrum.

Dependencies are inferred from the claim text.