Method for producing oligosaccharide having lewis x skeleton
AssigneeKirin Holdings Kabushiki Kaisha
InventorTomotoshi SUGITA
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AssigneeKirin Holdings Kabushiki Kaisha
InventorTomotoshi SUGITA
Estimating the term…
The present invention relates to a microorganism having an enhanced activity of a protein according to any one of the following [1] to [4] and improved productivity of an oligosaccharide having a Lewis X skeleton as compared with a parent strain: [1] a protein consisting of the amino acid sequence represented by SEQ ID NO: 2, [2] a mutant protein having an α1,3-fucosyl transferase activity and consisting of an amino acid sequence in which 1 to 20 amino acids are deleted, substituted, inserted, or added in the amino acid sequence represented by SEQ ID NO: 2, [3] a homologous protein having an α1,3-fucosyl transferase activity and consisting of an amino acid sequence having an identity of 90% or more with the amino acid sequence represented by SEQ ID NO: 2, and [4] a protein consisting of the amino acid sequence represented by SEQ ID NO: 24, 18, or 26.
A microorganism having an enhanced activity of a protein according to any one of the following [1] to [6] and improved productivity of an oligosaccharide having a Lewis X skeleton as compared with a parent strain:
Dependencies are inferred from the claim text.