Chemoenzymatic carboxylation compositions and methods

Abstract

A method of increasing the carbon content of an organic compound comprising carboxylating an organic compound characterized by the general formula R1—H and carbon dioxide in the presence of a biocatalyst under conditions suitable for the formation of a carboxylic acid characterized by the general formula R1—OOH, wherein R1 is a C1 to C30 organyl group; a C1 to C30 hydrocarbyl group, a C3 to C30 aromatic group; a C1 to C30 alkyl group, a C4 to C30 cycloalkyl group, a C4 to C30 substituted cycloalkyl group, a C3 to C30 aliphatic heterocyclic group, a C3 to C30 substituted aliphatic heterocyclic group, a C6 to C30 aryl group, a C6 to C30 substituted aryl group, a C3 to C30 heteroaryl group, or a C3 to C30 substituted heteroaryl group or combinations thereof.

Dependencies are inferred from the claim text.