Epitope of Regulatory T Cell Surface Antigen and Antibody Specifically Binding Thereto
AssigneeGood T Cells, Inc.
InventorsJung Ho Kim, Beom Seok Kim
Life of this patent
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Abstract
The present invention relates to an epitope of leucine-rich and immunoglobulin-like domains 1 (Lrig-1) protein, which is an antigen present on the surface of regulatory T cells, and an antibody or antigen-binding fragment specifically binding thereto.
Claims8
A method for preventing or treating cancer by decreasing phosphorylation of STAT3, the method comprising administering, to an individual, an antibody or antigen-binding fragment thereof that specifically binds to the Lrig-1 protein, the antibody or the antigen-binding fragment thereof comprising at least one polypeptide having an amino acid sequence of any of SEQ ID NOs:
- 4 to 29.
Dependencies are inferred from the claim text.