Antibodies targeting the b-cell receptor of chronic lymphocytic leukemia and uses thereof

An antibody having

• a heavy chain amino acid sequence as represented by SEQ ID NO:
• 1 and a light chain amino acid sequence of SEQ ID NO:
• 2, or
• a heavy chain amino acid sequence of SEQ ID NO:
• 11 and a light chain amino acid sequence of SEQ ID NO:
• 12;
• or
• comprising a variable heavy chain having a sequence selected from the list consisting of SEQ ID NO:
• 15 and SEQ ID NO:
• 20 in any combination with a variable light chain having a sequence selected from the list of SEQ ID NO:
• 16, SEQ ID NO:
• 17, SEQ ID NO:
• 18, and SEQ ID NO:
• 19.