Antagonists of the muscarinic acetylcholine receptor m4
AssigneeVanderbilt University
InventorsAaron M. Bender, Matthew Spock, Melissa A. Korkmaz-Vaisys, Cori A. Malinky, P. Jeffrey Conn, Craig W. Lindsley
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AssigneeVanderbilt University
InventorsAaron M. Bender, Matthew Spock, Melissa A. Korkmaz-Vaisys, Cori A. Malinky, P. Jeffrey Conn, Craig W. Lindsley
Estimating the term…
Disclosed herein are (6-(4-(trifluoromethyl)pyridin-3-yl)pyridazin-3-yl)octahydrocyclopenta[c]pyrrol-5-amine, (6-(4-(difluoromethyl)pyridin-3-yl)pyridazin-3-yl)octahydrocyclopenta[c]pyrrol-5-amine, and (6-(2-(trifluoromethyl)pyridin-3-yl)pyridazin-3-yl)octahydrocyclopenta[c]pyrrol-5-amine compounds, useful as antagonists of the muscarinic acetylcholine receptor M4 (mAChR M4). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and methods of treating disorders using the compounds and compositions.
A compound of formula (V):
Dependencies are inferred from the claim text.