Modular extracorporeal ambulatory lung assist device

A system for lung assist, comprising:

• a fiber bundle section comprising a fiber bundle housing defining a fiber bundle compartment therein, a fiber bundle positioned within the fiber bundle compartment, the fiber bundle comprising a plurality of hollow gas permeable fibers, the plurality of hollow gas permeable fibers being adapted to permit diffusion of gas between blood and an interior of the plurality of hollow gas permeable fibers, the plurality of hollow gas permeable fibers being positioned such that blood flows around the plurality of hollow gas permeable fibers when flowing through the fiber bundle compartment, the fiber bundle housing further comprising a gas inlet in fluid connection with the fiber bundle housing and in fluid connection with inlets of the plurality of hollow gas permeable fibers, a gas outlet in fluid connection with the fiber bundle housing and in fluid connection with outlets of the plurality of hollow gas permeable fibers, a blood outlet in fluid connection with a first end of the fiber bundle housing and a first interface disposed on a second end of the fiber bundle housing opposite the first end, wherein the first interface comprises a first connector configured to form a releasable connection with a second connector, and
• a base section comprising a housing comprising a pressurizing section including a pressurizing compartment and an interface section, the interface section including an extending section which is positioned at a lateral end of the pressurizing section and extends at an angle from the lateral end of the pressurizing section and a second interface formed on the extending section, the second interface including the second connector that is configured to form a releasable, sealing connection with the first connector of the first interface of the fiber bundle section such that the fiber bundle housing of the fiber bundle section extends substantially parallel to the pressurizing section, wherein the base section housing and the fiber bundle housing are separate elements connected by the releasable, sealing connection between the first and second connectors, a pressurizing mechanism within the pressurizing compartment, a blood inlet in fluid connection with the pressurizing compartment and a conduit in fluid connection with the pressurizing compartment at a first end thereof via which pressurized fluid exits the pressurizing compartment, wherein a second end of the conduit is placed in fluid connection with the second end of the fiber bundle when the fiber bundle section is connected to the base section via the first interface and the second interface.

A system for lung assist, comprising:

• a fiber bundle section comprising a fiber bundle housing defining a fiber bundle compartment therein, a fiber bundle positioned within the fiber bundle compartment, the fiber bundle comprising a plurality of hollow gas permeable fibers, the plurality of hollow gas permeable fibers being adapted to permit diffusion of gas between blood and an interior of the plurality of hollow gas permeable fibers, the plurality of hollow gas permeable fibers being positioned such that blood flows around the plurality of hollow gas permeable fibers when flowing through the fiber bundle compartment, the fiber bundle housing further comprising a gas inlet in fluid connection with the fiber bundle housing and in fluid connection with inlets of the plurality of hollow gas permeable fibers, a gas outlet in fluid connection with the fiber bundle housing and in fluid connection with outlets of the plurality of hollow gas permeable fibers, a blood outlet in fluid connection with a first end of the fiber bundle housing and a first interface disposed on a second end of the fiber bundle housing opposite the first end;
• and
• a base section comprising a housing comprising a pressurizing section including a pressurizing compartment and an interface section, the interface section including an extending section which is positioned at a lateral end of the pressurizing section and extends at an angle from the lateral end of the pressurizing section and a second interface formed on the extending section configured to form a releasable, sealing connection with the first interface of the fiber bundle section such that the fiber bundle housing of the fiber bundle section extends substantially parallel to the pressurizing section, wherein the base section housing and the fiber bundle housing are separate elements connected to one another only by the releasable, sealing connection between the first and second interfaces at the lateral end of the pressurizing section, a pressurizing mechanism within the pressurizing compartment, a blood inlet in fluid connection with the pressurizing compartment and a conduit in fluid connection with the pressurizing compartment at a first end thereof via which pressurized fluid exits the pressurizing compartment, wherein a second end of the conduit is placed in fluid connection with the second end of the fiber bundle when the fiber bundle section is connected to the base section via the first interface and the second interface.