COMPOSITIONS AND METHODS FOR FcRn-TARGETED INTRANASAL CORONAVIRUS VACCINATION
AssigneeUniversity of Maryland, College Park
InventorsXiaoping Zhu, Weizhong Li, Tao Wang
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Abstract
The present disclosure relates generally to novel recombinant coronavirus-based fusion proteins (“RBDs-IgG Fc protein” and “RBDs protein”) and vaccine compositions using the same, in which the fusion proteins comprise tandemly arranged coronaviruses receptor binding domains (RBDs). The present disclosure further provides methods and kits for immunizing a subject using the compositions.
Claims63
A recombinant coronavirus protein comprising one or more tandemly arranged coronavirus receptor binding domains (RBDs) fused to an IgG Fc domain (RBDs-IgG Fc protein).
A recombinant coronavirus protein comprising one or more tandemly arranged coronavirus RBDs (RBDs protein).
Dependencies are inferred from the claim text.