Pharmaceutical composition comprising ibrutinib
AssigneeSynthon BV
InventorsMarta VIVANCOS MARTINEZ, Lisardo ALVAREZ FERNANDEZ, Rohit KUMAR
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Abstract
The present invention relates to a tablet composition comprising Ibrutinib and one ore more pharmaceutically acceptable excipients. The invention further relates to the use of said composition as a medicament, particularly in the treatment of lymphocytic leukaemia (CLL), mantle cell lymphoma (MCL), Waldenström's macroglobulinaemia (WM) and chronic graft versus host disease (cGVHD).
Claims11
A high load tablet comprising from 60 to 85% by weight of Ibrutinib relative to the total weight of the tablet, from 1.5% to 3% by weight of sodium stearyl fumarate relative to the total weight of the tablet, and one or more pharmaceutically acceptable excipients.
Dependencies are inferred from the claim text.