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US 2025/0144098 A1Published application
Formulations of pyrimidine cyclohexyl glucocorticoid receptor modulators
AssigneeCorcept Therapeutics, Inc.
InventorsYip-Fong CHIA, Stephen ARBOLEDA, Yan ALSMEYER, Gordon DAVIS, Tyler CLIKEMAN
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Abstract
The present invention provides formulations of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
Claims25
A composition comprising:
- Compound I, (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione:
- in an amount from 15.0 to 32.0% (w/w);
- a poly[(methyl methacrylate)-co-(methacrylic acid)] in an amount from 15.0 to 32.0% (w/w);
- a sustaining polymer in an amount from 10.0 to 32.0% (w/w);
- microcrystalline cellulose in an amount from 10.0 to 25.0% (w/w);
- and
- croscarmellose sodium (Ac-Di-Sol) in an amount from 5.0 to 11.0% (w/w).
4 more elements
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Dependencies are inferred from the claim text.