Back to results
US 2025/0144090 A1Published application
Composition and method for treatment of depression and psychosis in humans
AssigneeGlytech, Inc.
InventorDaniel C. Javitt
Life of this patent
Estimating the term…
Abstract
This application relates to combination compositions for use in treatment of depression, and which can alleviate the anxiogenic side effects of certain antidepressant and antipsychotic medications. Methods for treatment of depression and medicament side effects, particular anxiety, akathisia, and associated suicidality are also described herein.
Claims17
A pharmaceutical composition for treatment of depression and associated suicidality comprising:
- D-cycloserine provided in a net NMDAR-antagonist effective amount sufficient to produce a sustained blood plasma concentration in excess of 25 microgram/mL but lower than 125 microgram/ml;
- and a therapeutically effective amount of roluperidone.
Dependencies are inferred from the claim text.