Method and composition for reducing myopia progression
AssigneeThe Hong Kong Polytechnic University
InventorsChuen LAM, Jing Fang BIAN, Yan Yin TSE, Chi ho TO
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Abstract
A method for reducing myopia progression. In particular, the method includes administering to a subject a compound represented by the following formula or a composition comprising an effective amount of the same: or a pharmaceutically accept salt thereof, in which the compound can target and inhibit catechol-O-methyltransferase, up-regulate retinal dopamine expression and change the choroidal thickness of a uvea of the subject, where an increase in choroidal thickness indicates a reduction in myopia progression.
Claims17
A method for reducing myopia progression comprising administering to a subject a composition comprising a therapeutically effective amount of a compound represented by the following formula:
- or a pharmaceutically accept salt thereof.
A composition comprising a therapeutically effective amount of a compound represented by the following formula:
- or a pharmaceutically accept salt thereof, for reducing myopia progression in a subject.
A method of increasing choroidal thickness of a uvea of a subject comprising contacting a compound represented by the following formula with a vitreous, cornea, or conjunctiva of the subject:
- or a pharmaceutically accept salt thereof.
Dependencies are inferred from the claim text.