US 2025/0143986 A1Published application

Composition for microneedle preparation, comprising cyclodextrin for retinol stabilization, and microneedle prepared with same composition

AssigneeRaphas Co., Ltd.

InventorsYee-Ram CHOI, Joo-Hyeon JANG, Sung-Su KIM, Gwon-Woo KIM, Boo-Yong LEE, Keun-Ho LEE, Jung-Hyun BAE, Chang-Yub SUNG, Soo-Kie LA, Hyun-Woo PARK, Do-Hyeon JEONG

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Abstract

The present invention relates to a retinol-loaded microneedle. The retinol-loaded microneedle according to the present invention contains retinol and a stabilizer therefor, which is an optimal combination for use in microneedles, in order to solve the instability of retinol. Accordingly, the retinol-loaded microneedle of the present invention achieves high transdermal delivery efficiency intrinsic for microneedle formulations and thus can maximize the effect of retinol on wrinkle reduction, etc.

Claims7

Dependent claims

A composition for a microneedle preparation, comprising:

retinol or a derivative thereof, cyclodextrin, and a biodegradable solidified material.

Dependencies are inferred from the claim text.

Facts

Application: 18/287,455Filed 11 Apr 2022
Priority: KR 10-2021-005030719 Apr 2021
Published: 8 May 2025
Term ends: Not estimatedThe source records don’t support an estimate.

Classification18 codes

A61K 8/342
Alcohols: alcohols having more than seven atoms in an unbroken chain
A61K 8/02
Cosmetics or similar toiletry preparations: characterised by special physical form
A61K 8/0204
Characterised by special physical form: specific forms not provided for by any of groups A61K8/0208 - A61K8/14
A61K 8/67
Containing organic compounds: vitamins

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