Cationic material for tooth desensitization, preparation method therefor, and application thereof

A preparation method for a cationic material for tooth desensitization, comprising the following steps:

• (1) dispersing, in deionized water, one or more of hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethyl cellulose, hyaluronic acid, alginate, lignin, dextran, soluble starch, polysaccharide, polyethylene glycol, branched polyethylene glycol, polyvinyl alcohol, a block copolymer of polyoxyethylene-polyoxypropylene ether, dimethyl diallyl ammonium chloride, carbomer, poly(methyl)acrylates, poly(methyl)acrylamides, polyethyleneimine, polyamino acid, gelatin, collagen, elastin, elastin-like polypeptides, silk fibroin, serum albumin, casein, soy protein, mucin, fibrin, and polynucleotide in any combination;
• stirring to dissolve the solute uniformly, and thereafter, respectively adding sodium hydroxide and a combined solution containing a modifier with one or more groups selected from primary amines, primary amine salts, secondary amines, secondary amine salts, tertiary amines, tertiary amine salts, quaternary amines, quaternary amine salts, piperidinium, pyrrolidine, imidazolium, and pyridinium;
• and letting them react;
• (2) neutralizing the reaction mixture obtained in the step (1) with hydrochloric acid, and then performing dialysis and freeze-drying to obtain a cationic material;
• and
• (3) preparing the cationic material obtained in the step (2) into a cationic material hydrogel solution with a mass concentration of 0.1% to 10%.