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US 2025/0143836 A1Published application
Systems and methods for optogenetic imaging using semi-kinematic coupling
AssigneeInscopix, Inc.
InventorsKelvin KAO, David PIGNATELLI, Mark O. TRULSON, Alice STAMATAKIS, Koen VISSCHER
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Abstract
Systems and methods for imaging using a microscope system comprising removeable or replaceable component parts. Such systems and methods employ semi-kinetic coupling for easy, tool-free attachment of the microscope system to a baseplate. Discussed systems and methods may include simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system.
Claims23
An imaging device, comprising:
- a) a baseplate configured to be attached to a subject having a target region to be imaged;
- b) a removeable and replaceable cable assembly;
- and
- c) a device body having a sensor cap assembly that comprises an image sensor configured to image the target region when the sensor cap assembly is connected to the device body,
- wherein the device body is connected to and separated from the baseplate in a tools-free reproducible manner, and
- wherein the device body comprises one or more V-grooves complementary to one or more bumps in the baseplate configured to have the device body be connected to and separated from the baseplate via kinematic coupling of the device body and the baseplate
- wherein the baseplate and device body comprise corresponding mating surfaces that mechanically prevent at least one of a rotational movement and an axial movement between the baseplate and the device body when the device body is attached to the baseplate.
4 more elements
An imaging device comprising:
- a) a baseplate configured to be attached to a subject having a target region to be imaged;
- b) a removable and replaceable cable assembly;
- c) a device body that includes a sensor cap assembly containing an image sensor configured to image a target region and that is configured to be connected to and separated from the baseplate in a tools-free reproducible manner;
- and
- d) an optical assembly contained in the device body and including:
- i. a first portion of an illumination optical arm of the imaging device comprising one or more illumination light-emitting elements and configured to direct imaging light along an optical path from the first portion of the illumination optical arm to the target region within a specified field-of-view (FOV);
- ii. a second portion of a stimulation optical arm of the imaging device comprising one or more stimulation light-emitting elements and configured to direct stimulation light to said target region;
- and
- iii. a third portion of an imaging optical arm of the imaging device comprising said image sensor and configured to receive light reflected, scattered, or emitted by said target region along an image collection pathway from the target region to the image sensor.
6 more elements
Dependencies are inferred from the claim text.