Pharmaceutical formulation for subcutaneous administration of proteins

A pharmaceutical formulation of a pharmaceutically active protein comprising:

• an effective amount of a protein or a combination of proteins,
• a chitosan A comprising between 90 and 100 mol % of D-glucosamine and between 0 and 15% of N-acetyl-D-glucosamine,
• at least one statistic polysaccharide B comprising D-glucosamine, N-acetyl-D-glucosamine and at least one saccharide unit of formula I:
• wherein:
• Rc is a hydrophilic group,
• Z is a linker being a single bond, a hydrocarbonated chain comprising between 1 and 12 carbon atoms, said chain being linear or branched, saturated or unsaturated and optionally comprising one or more heteroatoms, and
• one or more pharmaceutically acceptable excipients.