US 2025/0134715 A1 · METHODS FOR SELECTIVE ABERRATION CORRECTION IN CORNEAL LASER ABLATION

Abstract

Methods and systems for planning and performing a corneal laser ablation procedure that may comprise a wavefront aberrometer and a corneal topography measuring device. Data from each of these devices may be compared for generating an astigmatism treatment to be incorporated into a laser ablation treatment map. Corrections derived from epithelial thickness measurements may also be incorporated into the treatment map.

Claims60

Dependent claims

A method of performing a corneal laser ablation procedure on an eye of a subject, the method comprising:

generating a treatment map from acts comprising:
acquiring measurements of one or more lower order whole eye optical aberration characteristics at least in part via retinal reflection measurements and deriving therefrom a first astigmatism characteristic representative of a lower order whole eye astigmatism;
acquiring measurements of one or more lower order elevation characteristics of the anterior corneal surface of the eye at least in part from one or more of either tear film, anterior epithelium, and/or epithelium basement membrane reflection measurements and deriving therefrom a second astigmatism characteristic representative of a lower order anterior corneal surface astigmatism;
comparing the first astigmatism characteristic with the second astigmatism characteristic to generate an estimate of an amount of difference between lower order whole eye astigmatism and lower order anterior corneal surface astigmatism;
based at least in part on the generated estimate, determining a third astigmatism characteristic for inclusion in the generation of the treatment map, wherein the third astigmatism characteristic is determined using either (1) one or both of the first astigmatism characteristic and the second astigmatism characteristic or (2) a derivative of one or both of the first astigmatism characteristic and the second astigmatism characteristic;
and
generating the treatment map using at least in part the third astigmatism characteristic;
creating an ablation pattern that can be used by a corneal laser ablation device from the treatment map;
and
using a corneal laser ablation device to apply laser pulses to the eye in accordance with the ablation pattern.

7 more elements

A method of generating a treatment map in order to create an ablation pattern that can be used for performing a corneal laser ablation procedure on an eye, the method comprising:

measuring a dataset of lower and higher order whole eye optical aberration data;
measuring a corresponding dataset of lower and higher order anterior corneal surface aberration data;
comparing the dataset of anterior corneal surface aberration data with the corresponding dataset of whole eye optical aberration data;
based at least in part on the comparing, performing one or more of (a) through (f):
(a) selecting a subset of the measured corneal surface aberration dataset for a corresponding subset of lower order and/or higher order aberration treatment;
(b) selecting a subset of the measured whole eye optical aberration dataset for a corresponding subset of lower order and/or higher order aberration treatment;
(c) selecting a derivative determined at least in part from both the measured whole eye optical aberration dataset and the measured corneal surface aberration dataset for a subset of lower order and/or higher order aberration treatment;
(d) selecting a derivative determined from an algorithm using the selected subset of corneal surface aberration data and a corresponding selected subset of whole eye optical aberration data as inputs for a subset of lower order and/or higher order aberration treatment;
(e) selecting a derivative determined by an output of a computation that uses a first percentage of a subset of the measured corneal surface aberration dataset and a second percentage of a corresponding subset of the measured whole eye optical aberration dataset as inputs for a subset of lower order and/or higher order aberration treatment;
(f) selecting a derivative determined from an algorithm using the difference in a selected measured subset of whole eye optical aberration data and a selected measured subset of corneal surface aberration data as inputs for a subset of lower order and/or higher order aberration treatment;
using one or more of the chosen options to define a treatment set of lower order and/or higher order aberrations for correction;
and
combining the treatment set of lower order and/or higher order aberrations for correction to generate the treatment map.

10 more elements

Dependencies are inferred from the claim text.

Facts

Application

18/763,706Filed 3 Jul 2024

Priority

3 Jul 2023

Published

1 May 2025

Term ends

Not estimatedThe source records don’t support an estimate.

Classification9 codes

A61F 9/00804
For photoablation: refractive treatments
A61F 9/00814
For photoablation: laser features or special beam parameters therefor
A61B 3/1035
For determining refraction, e.g. refractometers or skiascopes: for measuring astigmatism
A61F 2009/00846
Feedback systems: eyetracking

Abstract

Claims60

Dependent claims

A method of performing a corneal laser ablation procedure on an eye of a subject, the method comprising:

generating a treatment map from acts comprising:
acquiring measurements of one or more lower order whole eye optical aberration characteristics at least in part via retinal reflection measurements and deriving therefrom a first astigmatism characteristic representative of a lower order whole eye astigmatism;
acquiring measurements of one or more lower order elevation characteristics of the anterior corneal surface of the eye at least in part from one or more of either tear film, anterior epithelium, and/or epithelium basement membrane reflection measurements and deriving therefrom a second astigmatism characteristic representative of a lower order anterior corneal surface astigmatism;
comparing the first astigmatism characteristic with the second astigmatism characteristic to generate an estimate of an amount of difference between lower order whole eye astigmatism and lower order anterior corneal surface astigmatism;
based at least in part on the generated estimate, determining a third astigmatism characteristic for inclusion in the generation of the treatment map, wherein the third astigmatism characteristic is determined using either (1) one or both of the first astigmatism characteristic and the second astigmatism characteristic or (2) a derivative of one or both of the first astigmatism characteristic and the second astigmatism characteristic;
and
generating the treatment map using at least in part the third astigmatism characteristic;
creating an ablation pattern that can be used by a corneal laser ablation device from the treatment map;
and
using a corneal laser ablation device to apply laser pulses to the eye in accordance with the ablation pattern.

7 more elements

A method of generating a treatment map in order to create an ablation pattern that can be used for performing a corneal laser ablation procedure on an eye, the method comprising:

measuring a dataset of lower and higher order whole eye optical aberration data;
measuring a corresponding dataset of lower and higher order anterior corneal surface aberration data;
comparing the dataset of anterior corneal surface aberration data with the corresponding dataset of whole eye optical aberration data;
based at least in part on the comparing, performing one or more of (a) through (f):
(a) selecting a subset of the measured corneal surface aberration dataset for a corresponding subset of lower order and/or higher order aberration treatment;
(b) selecting a subset of the measured whole eye optical aberration dataset for a corresponding subset of lower order and/or higher order aberration treatment;
(c) selecting a derivative determined at least in part from both the measured whole eye optical aberration dataset and the measured corneal surface aberration dataset for a subset of lower order and/or higher order aberration treatment;
(d) selecting a derivative determined from an algorithm using the selected subset of corneal surface aberration data and a corresponding selected subset of whole eye optical aberration data as inputs for a subset of lower order and/or higher order aberration treatment;
(e) selecting a derivative determined by an output of a computation that uses a first percentage of a subset of the measured corneal surface aberration dataset and a second percentage of a corresponding subset of the measured whole eye optical aberration dataset as inputs for a subset of lower order and/or higher order aberration treatment;
(f) selecting a derivative determined from an algorithm using the difference in a selected measured subset of whole eye optical aberration data and a selected measured subset of corneal surface aberration data as inputs for a subset of lower order and/or higher order aberration treatment;
using one or more of the chosen options to define a treatment set of lower order and/or higher order aberrations for correction;
and
combining the treatment set of lower order and/or higher order aberrations for correction to generate the treatment map.

10 more elements

Dependencies are inferred from the claim text.

Methods for selective aberration correction in corneal laser ablation

Life of this patent

Abstract

Claims60

Methods for selective aberration correction in corneal laser ablation

Life of this patent

Abstract

Claims60