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AssigneeFujifilm Diosynth Biotechnologies UK Limited
InventorsCharles Heise, Jonathan Haigh, Tibor Nagy, James Pullen, Andrew Topping
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Apparatus for processing a liquid comprising a target substance, preferably a biomolecule, is provided. The apparatus comprises at least a first and a second means for carrying out a unit operation, each means for carrying out a unit operation comprising a feed for a liquid in fluid connection with the inlet of a flow-controller comprising a variable flow inlet valve and an outlet, wherein at least one of the means for carrying out a unit operation comprises feeds for at least two liquids, the feeds being in fluid connection with the inlets of a multiple inlet flow-controller comprising two or more variable flow inlet valves for dosing the at least two liquids, the flow-controller also comprising an outlet; a feed for a liquid feedstock comprising the target substance in fluid connection with the outlet from the flow-controller thereby to enable combination of the feed for a liquid comprising the target substance with the mixed bioprocessing liquids to produce a device feed; a device for achieving a processing operation comprising a device inlet and a device outlet, the device inlet being in fluid connection with the device feed; and a means for imparting flow through the flow controller and from the feed for the liquid feedstock through the processing device via the device inlet; and wherein the feed for a liquid feedstock comprising the target substance for the second means for carrying out a unit operation comprises the outlet from the first means for carrying out a unit operation.
Apparatus for processing a liquid comprising a target substance, said apparatus comprising at least a first and a second means for carrying out a unit operation, each means for carrying out a unit operation comprising:
Apparatus according to either preceding claim, wherein the means for imparting flow comprises a single pump, located downstream of the fluid connection between the connection between the feedstock and the outlet from the flow-controller.
Apparatus according to any preceding claim, wherein the means for carrying out a unit operation are connected in series, with the feed for a liquid feedstock comprising the target substance for a subsequent means for carrying out a unit operation comprising the outlet from the preceding means for carrying out a unit operation.
Apparatus according to any preceding claim, wherein each unit operation differs from the other unit operations.
Apparatus according to any preceding claim, wherein each means for carrying out a unit operation comprises substantially the same flow path.
Apparatus for preparing a liquid mixture, said apparatus comprising:
A process for preparing a biomolecule, comprising processing the biomolecule using apparatus according to any preceding claim.
Dependencies are inferred from the claim text.