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US 2025/0115545 A1Published application
Terpene-containing lipidoids for gene delivery
AssigneeUniversity of San Diego
InventorsPeter M. Iovine, Gopi Nath Vemuri
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Abstract
Terpene-containing lipidoid compounds, methods of preparing such compositions, and the use of these, compositions in gene delivery applications are disclosed.
Claims33
A compound of Formula (I), Formula (II) or Formula (III):
- wherein:
- A is A′ or A″,
- A′ is:
- and
- A″ is:
- B is B′ or B″,
- B′ is:
- and
- B″ is:
- wherein when A is A′, then B is B′, and wherein when A is A″, then B is B″;
- C is:
- n is an integer between 1 to 6;
- each Z is independently H or —S—R1;
- each R1 is independently selected from:
- alkyl,
- each R2 or R3 is independently selected from hydrogen, C1-C6 alkyl, C1-C6 alkenyl, aralkyl, or hydroxyalkyl;
- each R4 is hydrogen or C1-C3 alkyl;
- each R5 is
- each R6 is
- each m is an integer independently selected from 1-10;
- and
- each q is an integer independently selected from 1-200.
19 more elements
Dependencies are inferred from the claim text.