Promoter for the expression of genes in particular cnr1-positive cells in mouse cortex
AssigneeFriedrich Miescher Institute for Biomedical Research
InventorsGeorg KELLER, Hassana OYIBO
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AssigneeFriedrich Miescher Institute for Biomedical Research
InventorsGeorg KELLER, Hassana OYIBO
Estimating the term…
The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1, or of a nucleic acid sequence of at least 1400 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule leads to the specific expression in mouse cortex of an exogenous gene in a particular population of CNR1-positive cells when a nucleic acid sequence coding for said exogenous gene is operatively linked to said isolated nucleic acid molecule, said particular population of CNR1-positive cells being characterized in that it also expresses EFHD1, ENPP6 and GJC2.
An isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1, or a nucleic acid sequence of at least 1400 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule leads to the specific expression in mouse cortex of an exogenous gene in a particular population of CNR1-positive cells when a nucleic acid sequence coding for said exogenous gene is operatively linked to said isolated nucleic acid molecule, said particular population of CNR1-positive cells being characterized in that it also expresses EFHD1, ENPP6 and GJC2.
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