Systems and methods for designing and conducting clinical trials and biomarker validation studies

A system for performing a clinical trial or biomarker validation study, the system comprising one or more computer processors programmed to perform operations comprising:

• obtaining access to a computer-implemented model that was trained using training data comprising a plurality of records for a plurality of individuals, each record comprising (i) values for a plurality of features for a respective individual from the plurality of individuals and (ii) a label providing an indication of a disease state for the respective individual;
• providing, to the trained computer-implemented model, a plurality of sets of values for the plurality of features, each set of values corresponding to a candidate individual from a set of candidate individuals;
• receiving, from the trained computer-implemented model, a prediction of a disease state for each set of values;
• identifying, from the predictions of the disease state, a group of participants from the set of candidate individuals;
• and
• facilitating at least one of a clinical trial or a biomarker validation study involving the group of participants.