Method for improving throughput of compound-protein interaction experiments

A method for improving a throughput of compound-protein interaction experiments, comprising:

• composing n types of compounds to be tested into m mixture systems, each of the m mixture systems comprising at least two of the n types of compounds to be tested, wherein the compounds to be tested comprised in different mixture systems have different types, and a difference value in type of the compounds to be tested comprised in different mixture systems is within a first preset range, a same compound to be tested is comprised in at least two different mixture systems, a difference value in number of the mixture systems for each compound to be tested is within a second preset range, and a difference value in number of the compounds to be tested comprised in each mixture system is within a third preset range;
• preparing m portions of target solutions according to the m mixture systems, wherein each of the m portions of the target solutions contains all of the compounds to be tested comprised in the mixture system and a target protein;
• measuring, in each of the m portions of the target solutions, a response value of each mixture system' ability to interact with the target protein;
• and
• determining, according to the response value of each mixture system' ability to interact with the target protein, an interaction between any of the compounds to be tested comprised in each mixture system and the target protein.