Method and device for drug screening

A method for testing the sensitivity of a primary tumor cell to an anti-tumor drug, comprising the following steps:

• (1) transferring a primary tumor cell into an implant device;
• (2) implanting the implant device comprising the primary tumor cell into an animal subcutaneously;
• (3) administering an anti-tumor drug to the animal;
• and
• (4) determining the sensitivity of the primary tumor cell to the anti-tumor drug by measuring the proliferation of cells exposed to drug relative to the proliferation of a control, wherein the primary tumor cell is obtained from an ex vivo tumor tissue sample and has been digested and sorted using CD45 cells sorting magnetic beads and fibroblast sorting magnetic beads;
• and
• wherein the magnetic beads comprises CD45 cells sorting magnetic beads and fibroblasts sorting magnetic beads to remove CD45 cells and fibroblasts from the primary tumor cells.