System for electrospray ionization with integrated lc column and electrospray emitter
AssigneeDionex Corporation
InventorsBrandon Howard Robson, Xuefei Sun, Carla Marie Medlin, Shane Bechler
Life of this patent
Estimating the term…
Loading patent…
AssigneeDionex Corporation
InventorsBrandon Howard Robson, Xuefei Sun, Carla Marie Medlin, Shane Bechler
Estimating the term…
An integrated system for liquid separation and electrospray ionization includes a capillary high-pressure liquid chromatography (HPLC) column with one end drawn to an electrospray ionization (ESI) tip with at least a portion of the capillary HPLC column coiled into a loop. The integrated system further includes an outer electrically conductive sheath adapted for insertion within a holder having a high-voltage contact point. The electrically conductive sheath is adapted to contact the high-voltage contact point and provide an electrical connection to enable the emitter-enabled capillary column to receive a high voltage. The electrically conductive sheath has a recess to receive the high-voltage contact point. The integrated system also includes a fitting coupled to the capillary HPLC column at an end distal from the ESI tip. The fitting is adapted for connection to a liquid chromatography system. The fitting electrically connected to the outer electrically conductive sheath.
An integrated system for liquid separation and electrospray ionization, comprising:
The integrated system according to claim 8, wherein the electrically conductive ball fits in the recess in the outer surface of the electrically conductive sheath, and wherein the recess is a circumferential groove.
The integrated system according to claim 10, wherein the electrically conductive sheath is electrically coupled to an electrically conductive union wherein the electrically conductive union is in direct contact with the eluent moving through the emitter-enabled capillary column.
Dependencies are inferred from the claim text.