Method for detecting anti-sars-cov-2 spike (s) immunoglobulins
AssigneeNovavax, Inc.
InventorsJoyce S. PLESTED, Raj KALKERI
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Abstract
Disclosed are methods for detecting if a biological sample (e.g., serum, blood, plasma) contains antibodies against SARS-CoV-2 S glycoproteins comprising: (i) providing a surface coated with a SARS-CoV-2 S glycoprotein; (ii) exposing the surface to the biological sample; (iii) exposing the surface to a secondary antibody; and (iv) detecting the secondary antibody that is bound to the surface; wherein the biological sample contains antibodies that bind to the SARS-CoV-2 S glycoprotein if secondary antibody is detected.
Claims20
A method for determining if a biological sample contains antibodies that bind to the SARS-CoV-2 Spike (S) glycoprotein, comprising:
- (i) providing a surface coated with a SARS-CoV-2 S glycoprotein;
- (ii) exposing the surface to the biological sample;
- (iii) exposing the surface to a secondary antibody;
- and
- (iv) detecting the secondary antibody that is bound to the surface;
- wherein the biological sample contains antibodies that bind to the SARS-CoV-2 S glycoprotein if the secondary antibody is detected.
Dependencies are inferred from the claim text.