Lateral flow assay by using carboxyl latex beads and biotin-polystreptavidin for the detection of covid-19 infection and diagnostic kit using the lateral flow assay

Abstract

The systems and methods herein are directed to carboxylated latex beads and biotin-polysterptavidin as a label material for fluorescence lateral flow assay (LFA) for the diagnosis of SARS-Cov-9 with increased sensitivity. The carboxylated latex and biotin-polystreptavidin instantly increases the fluorescence intensity and the resulting signal enhancement significantly increases sensitivity for analyte detection. The LFA can also be used for the detection of SARS-Cov-2 and as rapid testing kit of COVID-19. The LFA kit allows detection of nucleocapsid protein of SARS-Cov-2 as little as 0.1 ng/ml and as a point of care testing of COVID-19.

Dependencies are inferred from the claim text.