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US 2025/0085274 A1Published application
Brevetoxin detection device, system, and method
OwnerDana L. Wetzel, Tracy A. Sherwoodinventors
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Abstract
A method to detect the presence of parent brevetoxin (BT) and brevetoxin metabolites (BTXs) in shellfish and aquatic samples is provided. The method may include contacting a sample with a binding molecule comprising an aptamer, and determining if the binding molecule binds a Brevetoxin antigen in the sample.
Claims15
A binding molecule for use in detection of brevetoxins in a sample, the binding molecule comprising:
- an aptamer configured to bind to a brevetoxin antigen;
- and
- a detection component having a detection property, the detection component being operably coupled to an aptamer and configured to facilitate detection of a brevetoxin in the sample, via the detection property, upon binding of an aptamer to a brevetoxin antigen.
A method of detecting a brevetoxin in a sample, the method comprising:
- applying a detector solution to the sample to cause an aptamer of a binding molecule of the detector solution to bind with a targeted brevetoxin antigen, wherein, upon binding of the aptamer to the brevetoxin antigen, a detection property of the detection component of the aptamer is activated;
- detecting, via a sensor, a response signal from the sample based on the detection property;
- and
- determining, by control circuitry, a presence of the brevetoxin in the sample based on the response signal from the sample.
1 more element
A test kit for detecting a brevetoxin in a sample, the test kit comprising:
- a holder configured to receive the sample;
- and
- a detector solution comprising a binding molecule;
- wherein the molecule comprises:
- an aptamer configured to bind to the brevetoxin antigen within the sample;
- and
- a detection component having a detection property, the detection component being operably coupled to the aptamer and configured to facilitate detection of a brevetoxin in the sample, via the detection property, upon binding of an aptamer to a brevetoxin antigen.
4 more elements
Dependencies are inferred from the claim text.