Tissue Cutting Assembly And Associated Method Of Use

A method of preparing desired sized and shaped tissue samples from a tissue sample using a frame, a tissue cutting guide, and a substrate, the frame having an inner perimeter defining an opening, and the tissue cutting guide having an external perimeter complimentary in configuration to the internal perimeter and defining a plurality of slits extending therethrough, said method comprising the steps of:

• disposing the tissue sample on the substrate;
• disposing the frame on the substrate such that the tissue sample is held stationary by the frame and such that a portion of the tissue sample is visible and accessible through the opening;
• securing the frame to the substrate;
• disposing the tissue cutting guide within the opening of the frame in any one of a plurality of positions relative to the frame, wherein the external perimeter of the tissue cutting guide at least partially abuts the internal perimeter of the frame to prevent rotational movement of the tissue cutting guide relative to the frame and the substrate;
• and
• allowing a user to apply desired cuts to the tissue sample through the spaced apart slits.

The method of claim 19, wherein said step of cutting the tissue sample while the tissue cutting guide is in the second position comprises the steps of:

• (e) inserting a blade of a cutting device within one of the slits of the plurality of slits;
• and
• (f) moving the blade of the cutting device along the length of the one slit to cut the tissue sample. 21 The method of claim 20, wherein the step of cutting the tissue sample while the tissue cutting guide is in the second position further comprises the steps of:
• (g) removing the blade of the cutting device from within the one slit;
• and
• (h) optionally repeating steps (e)-(f) for one or more additional slits of the plurality of slits.