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US 2025/0084483 A1Published application
Methods of Detecting Bladder Cancer
AssigneeCepheid
InventorsLeena McCann, Stacey Ellen Wallace, Edwin Wei-Lung Lai, Russell Higuchi
Life of this patent
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Abstract
Compositions and methods for detecting bladder cancer are provided. In some embodiments, methods of detecting low grade bladder cancer are provided. In some embodiments, methods of monitoring recurrence of bladder cancer are provided. In some embodiments, the methods comprise detecting androgen receptor (AR) and/or uroplakin 1B (UPK1B).
Claims20
1-73. (canceled)
A composition comprising a set of bladder cancer marker primer pairs comprising:
- a primer pair for detecting corticotrophin releasing hormone (CRH);
- and
- at least one additional primer pair for detecting a marker selected from insulin-like growth factor 2 (IGF2), uroplakin 1B (UPK1B), and annexin 10 (ANXA10);
- and
- wherein the primer pair for detecting CRH comprises a first primer comprising at least 8 contiguous nucleotides of SEQ ID NO:
- 35 or SEQ ID NO:
- 36.
4 more elements
Dependencies are inferred from the claim text.