Nucleic acid detection system and method for detecting influenza
AssigneeTriad National Security, LLC
InventorsHong Cai, Jian Song
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AssigneeTriad National Security, LLC
InventorsHong Cai, Jian Song
Estimating the term…
The invention provides a rapid, sensitive and specific nucleic acid detection system which utilizes isothermal nucleic acid amplification in combination with a lateral flow chromatographic device, or DNA dipstick, for DNA-hybridization detection. The system of the invention requires no complex instrumentation or electronic hardware, and provides a low cost nucleic acid detection system suitable for highly sensitive pathogen detection. Hybridization to single-stranded DNA amplification products using the system of the invention provides a sensitive and specific means by which assays can be multiplexed for the detection of multiple target sequences.
A lateral flow device for detection of a target nucleic acid in a sample, the lateral flow device comprising:
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