US 2025/0084131 A1 · T-CELL EPITOPE POLYPEPTIDE OF FOOT AND MOUTH DISEASE VIRUS AND USES THEREOF

Abstract

A T-cell epitope polypeptide of foot and mouth disease virus (FMDV) having an amino acid sequence represented by one of SEQ ID Nos: 1-11: SEQ ID NO: 1: KGKPFNSKVIIATTNLYS; SEQ ID NO: 2: PLQNVYQLVQEVIDRVEL; SEQ ID NO: 3: VVMDDLGQNPDGKDFKYF; SEQ ID NO: 4: YNQQTVVVMDDLGQNPDG; SEQ ID NO: 5: GRTDSVWYCPPDPDHFDG; SEQ ID NO: 6: RGKSGQGKSFLANVLAQA; SEQ ID NO: 7: PDFNRLVSAFEELATGVK; SEQ ID NO: 8: AIRTGLDEAKPWYKLIKL; SEQ ID NO: 9: MSTKHGPDFNRLVSAFEE; SEQ ID NO: 10: MLDGRTMTDSDYRVF; and SEQ ID NO: 11: VLDEVIFSKHKGDTK.

Claims10

Dependent claims

A T-cell epitope polypeptide of foot and mouth disease virus (FMDV), the epitope polypeptide having an amino acid sequence represented by one of SEQ ID Nos:

1-11:
SEQ ID NO:
1:
KGKPFNSKVIIATTNLYS;
SEQ ID NO:
2:
PLQNVYQLVQEVIDRVEL;
SEQ ID NO:
3:
VVMDDLGQNPDGKDFKYF;
SEQ ID NO:
4:
YNQQTVVVMDDLGQNPDG;
SEQ ID NO:
5:
GRTDSVWYCPPDPDHFDG;
SEQ ID NO:
6:
RGKSGQGKSFLANVLAQA;
SEQ ID NO:
7:
PDFNRLVSAFEELATGVK;
SEQ ID NO:
8:
AIRTGLDEAKPWYKLIKL;
SEQ ID NO:
9:
MSTKHGPDFNRLVSAFEE;
SEQ ID NO:
10:
MLDGRTMTDSDYRVF;
and
SEQ ID NO:
11:
VLDEVIFSKHKGDTK.

32 more elements

Dependencies are inferred from the claim text.

Facts

Application

18/824,867Filed 4 Sep 2024

Priority

CN 202311180688.113 Sep 2023

Published

13 Mar 2025

Term ends

Not estimatedThe source records don’t support an estimate.

Classification10 codes

C07K 14/005
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from viruses
A61K 39/12
Medicinal preparations containing antigens or antibodies: viral antigens
A61K 39/135
Picornaviridae, e.g. calicivirus: foot- and mouth-disease virus
A61K 2039/552
Characterised by the host/recipient, e.g. newborn with maternal antibodies: veterinary vaccine

T-cell epitope polypeptide of foot and mouth disease virus and uses thereof

Life of this patent

T-cell epitope polypeptide of foot and mouth disease virus and uses thereof

Life of this patent

Abstract

Claims10