System for remote drug monitoring and titration

A computer-implemented method of providing remote antiarrhythmic drug (AAD) initiation using a defibrillator device, the method comprising:

• receiving electrocardiogram at least one electrocardiogram (ECG) source;
• cleansing said electrocardiographic data;
• extracting ECG segments from cleansed electrocardiographic data based on ECG channel electrode(s) of interest;
• providing one or more baseline models trained with annotated segments to generate interpreted heart rhythm or rate based on the extracted ECG segments;
• selecting an image processing model based on the interpreted heart rhythm or rate;
• applying the selected image processing model to the cleansed electrocardiographic data, wherein the image processing model outputs a corrected QT interval (QTc) measurement, wherein the corrected QTc measurement meets a threshold value;
• and
• applying the QTc measurement with the defibrillator device to provide the remote AAD initiation, wherein the defibrillator is configured to utilize pulse sensor data to distinguish between perfusing and pulseless ventricular arrhythmias in relation to the QTc measurement.

A system for clinical decision-making using a mobile cardiac telemetry (MCT) device, the system comprising:

• one or more modules configured to interface with a patient via a secured communication, wherein said one or more modules are adapted to receive, through the secured communication, electrocardiogram (ECG) telemetry data from the patient for a predetermined time period until a clinical decision is made, and
• wherein said one or more modules are further configured to exhibit arrhythmia information to an interface based on input from the MCT device, wherein the MCT device is adapted to provide the arrhythmia information in accordance with the clinical decision;
• and
• another module of said one or more modules configured to generate one or more corrected QT interval (QTc) measurements, at least one QTc measurement meets a threshold value, based on the received ECG data and arrhythmia information to provide clinical decision-making based on said one or more QTc measurements within the predetermined time period.