A method of isolating and ablating a lumen comprising:
- a) providing a lumen treatment apparatus comprising:
- i) an access port configured to extend through a lumen wall and into a lumen, said access port comprising:
- a lumen end configured for locating within said lumen;
- and
- an exposed end configured for locating outside of said lumen;
- ii) an access balloon interface;
- iii) an access balloon attached to the access port and configured to inflate via said access balloon interface within said lumen;
- wherein the access balloon is a toroid balloon having an access balloon aperture;
- iv) an integrated isolation component comprising:
- an isolation balloon assembly comprising:
- isolation balloon inflation conduit configured to extend through the access port, through the access balloon aperture and into the lumen to a distal end of the isolation balloon assembly;
- an isolation balloon coupled to the isolation balloon inflation conduit and configured to be inflated within the lumen to create an isolated lumen between said isolation balloon and the access balloon;
- iv) an ablation treatment assembly comprising:
- an ablation treatment apparatus configured to extend through the access port, through the access balloon aperture and into the lumen, said ablation treatment apparatus comprising:
- an agent conduit with a plurality of agent apertures configured through the agent conduit an offset distance from an extended end of the agent conduit;
- an ablation implement coupled to the agent conduit and extending radially outward from the agent conduit and configured to contact an interior surface of said lumen wall to ablate the lumen wall;
- and
- v) a therapeutic agent configured to be delivered into the lumen through the agent apertures in the agent conduit;
- and
- b) locating the access port through the lumen wall to position said lumen end within said lumen and said exposed end outside of said lumen;
- c) inflating the access balloon via the access balloon interface to secure the access port in a fixed position with respect to the lumen;
- d) introducing the isolation balloon inflation conduit of the integrated isolation component through access port, into the lumen and moving the distal end of the isolation balloon assembly an offset distance from the access balloon;
- e) inflating the isolation balloon via the isolation balloon inflation conduit and the isolation balloon interface to produce an isolation lumen between the isolation balloon and the access balloon;
- f) introducing the ablation treatment apparatus through the access port and into the lumen;
- g) aspirating the isolated lumen;
- h) infusing therapeutic agent into the isolated lumen;
- i) ablating the isolated lumen by moving ablation treatment assembly back and forth within the isolated lumen;
- j) removing the ablation treatment apparatus from the isolated lumen;
- k) deflating the isolation balloon;
- l) removing the isolation balloon inflation conduit and isolation balloon from the lumen through the access port;
- m) deflating the access balloon;
- and
- n) removing the access port to produce an ablated lumen.