A system for guiding a user holding in one hand a probe configured for ultrasound observation of a body of a patient, the system comprising the probe provided with a first object secured to the probe, the first object comprising first markers on the surface of the first object, the system also comprising a second object comprising second markers on the surface of the second object, the system comprising a support placed at a predetermined point of the surface of the patient's body observed with the probe, the second object being placed on a surface of the support configured to maintain the second object in a predetermined position and orientation of the second object relative to a fixed reference frame relative to the patient's body, the system further comprising a camera configured to observe in its field the probe, the first object, and the second object, the system comprising a display device configured to receive at least one image acquired by the camera, the display device being configured to display the at least one image acquired by the camera, and to display in the at least one image in augmented reality at least one first point corresponding to a vertex of a polygon disposed in a first plane transverse to a recorded direction of the probe, so that a central area of the polygon is crossed by a straight line parallel to the recorded direction of the probe and passing through the recorded position of the probe, and to display in the at least one image in augmented reality at least one second point corresponding to the vertex of the polygon disposed in a second plane transverse to the current direction of the probe, so that a central area of the polygon is crossed by a straight line parallel to the current direction of the probe and passing through the current position of the probe, the user holding the probe in a hand being guided by the display to make the at least one first point coincide with the at least one second point in the at least one displayed image, by displacing the probe to a new current position and a new current direction so as to gradually make the new current position and the new current direction of the probe coincide with the recorded position and the recorded direction of the probe.