Method for transferring a pressure wave from peripheral site to central site

A non-transitory computer-readable medium having executable instructions stored thereon that, when executed by a processor, cause the processor to perform operations comprising:

• obtaining a time-domain representation of a first pulse pressure waveform signal of a brachial artery of a subject;
• converting the time-domain representation of the first pulse pressure waveform signal to a frequency-domain representation of the first pulse pressure waveform signal;
• selecting a first plurality of frequency components of the frequency-domain representation of the first pulse pressure waveform signal;
• predicting, using a non-linear mapping, based on the first plurality of frequency components, a second plurality of frequency components of a frequency-domain representation of a second pulse pressure waveform signal of an ascending aorta or a left ventricle of the subject;
• and
• converting the frequency-domain representation of the second pulse pressure waveform signal to a time-domain representation of the second pulse pressure waveform signal.

A method, comprising:

• obtaining, using a brachial cuff, a time-domain representation of a first pulse pressure waveform signal of a brachial artery of a subject;
• reconstructing, using a frequency-domain representation of the first pulse pressure waveform signal, a frequency-domain representation of a second pulse pressure waveform signal of a left ventricle (LV) of the subject;
• obtaining, using the frequency-domain representation of the second pulse pressure waveform signal of the LV of the subject, an LV pressure curve of the subject in the time domain;
• capturing, using an imaging device, one or more images of the LV of the subject;
• measuring, using the one or more images of the LV, an LV volume curve of the subject;
• and
• obtaining, using the LV pressure curve and the LV volume curve, an LV pressure-volume curve.