Fourier-domain OCT apparatus for Optoretinography

A Fourier-domain optical coherence tomography, FD-OCT, apparatus arranged to acquire optoretinography, ORG, data that is indicative of a physiological response of a retina of an eye of a subject to an optical stimulus, the FD-OCT apparatus comprising:

• an optical system operable to apply the optical stimulus to the retina;
• an FD-OCT imaging system operable to acquire OCT data by imaging a portion of the retina;
• and
• a controller arranged to:
• control the FD-OCT imaging system to acquire OCT data of a plurality of portions of the retina such that, for each portion of the plurality of portions of the retina, at least some of the OCT data acquired from the portion is acquired after a respective optical stimulus has been applied to the portion by the optical system;
• generate, based on the acquired OCT data, respective ORG data for each portion of the plurality of portions of the retina which is indicative of the respective response of the portion of the retina to the optical stimulus applied to the portion of the retina;
• store, for each portion of the plurality of portions of the retina, the respective ORG data generated from OCT data acquired from the portion in association with a respective indication of a location of the portion on the retina;
• and
• acquire data indicating how measurements of the subject's ability to see optical stimuli that are confined to respective different portions of the retina of the eye at different respective locations on the retina are distributed over the at least a part of the retina of the eye.

A computer-implemented method of controlling a Fourier-domain optical coherence tomography, FD-OCT, apparatus to acquire optoretinography, ORG, data that is indicative of a physiological response of a retina of an eye of a subject to an optical stimulus, the FD-OCT apparatus comprising an optical system operable to apply the optical stimulus to the retina and an FD-OCT imaging system operable to acquire OCT data by imaging a portion of the retina, the method comprising:

• controlling the FD-OCT imaging system to acquire OCT data of a plurality of portions of the retina such that, for each portion of the plurality of portions of the retina, at least some of the OCT data acquired from the portion is acquired after a respective optical stimulus has been applied to the portion by the optical system;
• generating, based on the acquired OCT data, respective ORG data for each portion of the plurality of portions of the retina which is indicative of the respective response of the portion of the retina to the optical stimulus applied to the portion of the retina;
• and
• storing, for each portion of the plurality of portions of the retina, the respective ORG data generated for the portion in association with a respective indication of a position in a visual field of the eye of a point that is optically conjugate with a corresponding position of the portion on the retina.

A computer-implemented method of controlling a Fourier-domain optical coherence tomography, FD-OCT, apparatus to acquire optoretinography, ORG, data that is indicative of a physiological response of a retina of an eye of a subject to an optical stimulus, the FD-OCT apparatus comprising an optical system operable to apply the optical stimulus to the retina and an FD-OCT imaging system operable to acquire OCT data by imaging a portion of the retina, the method comprising:

• controlling the FD-OCT imaging system to acquire OCT data of a plurality of portions of the retina such that, for each portion of the plurality of portions of the retina, at least some of the OCT data acquired from the portion is acquired after a respective optical stimulus has been applied to the portion by the optical system;
• generating, based on the acquired OCT data, respective ORG data for each portion of the plurality of portions of the retina which is indicative of the respective response of the portion of the retina to the optical stimulus applied to the portion of the retina;
• storing, for each portion of the plurality of portions of the retina, the respective ORG data generated from OCT data acquired from the portion in association with a respective indication of a location of the portion on the retina;
• and
• acquiring data indicating how measurements of the subject's ability to see optical stimuli that are confined to respective different portions of the retina of the eye at different respective locations on the retina are distributed over the at least a part of the retina of the eye.

A computer program comprising computer-readable instructions which, when executed by a computer, cause the computer to perform a method, comprising:

• controlling the FD-OCT imaging system to acquire OCT data of a plurality of portions of the retina such that, for each portion of the plurality of portions of the retina, at least some of the OCT data acquired from the portion is acquired after a respective optical stimulus has been applied to the portion by the optical system;
• generating, based on the acquired OCT data, respective ORG data for each portion of the plurality of portions of the retina which is indicative of the respective response of the portion of the retina to the optical stimulus applied to the portion of the retina;
• and
• storing, for each portion of the plurality of portions of the retina, the respective ORG data generated for the portion in association with a respective indication of a position in a visual field of the eye of a point that is optically conjugate with a corresponding position of the portion on the retina.