Methods and Apparatus to Separate Biological Entities

A magnetic device comprising:

• a holder;
• a plurality of conduits mounted on the holder and configured to flow a fluid sample containing magnetically labeled biological objects;
• a plurality of magnetic assemblies, each magnetic assembly including:
• a soft magnetic center pole having a bottom end and a tapered tip end;
• first and second soft magnetic side poles disposed on opposite sides of the soft magnetic center pole and respectively having first and second bottom ends, the first and second soft magnetic side poles respectively having first and second top ends that are bent towards the soft magnetic center pole and are positioned above the tapered tip end;
• and
• a magnetic flux source generating a magnetic flux in the soft magnetic center pole and the first and second soft magnetic side poles, the magnetic flux being concentrated from the bottom end to the tapered tip end of the soft magnetic center pole and divided between the first and second top ends,
• wherein each conduit is disposed in a gap formed between the tapered tip end and the first and second top ends of a respective magnetic assembly of the plurality of magnetic assemblies.