Imaging system and sequencing system

Abstract

The present disclosure discloses an imaging system and a sequencing system. The imaging system comprises an objective lens and image sensors. The image sensor comprises a first set of image sensors and a second set of image sensors. A first set of tube lenses are arranged between the objective lens and the first set of image sensors and are configured for enabling the imaging system to have a first depth of field when imaging a first surface; a second set of tube lenses are arranged between the objective lens and the second set of image sensors and are configured for enabling the imaging system to have a second depth of field when imaging a second surface. The first depth of field and the second depth of field are both smaller than a distance of displacement from the first surface to the second surface along the optical axis of the objective lens. The imaging system of the present disclosure can simultaneously achieve the acquisition of optical signals on two surfaces of a sample of interest and imaging. This allows the imaging system to detect biomolecules on the two surfaces of the sample of interest, identify the type of bases in the biomolecules, and acquire the base sequences, thus reducing the detection time and improving the detection efficiency and the sequencing throughput.

Dependencies are inferred from the claim text.