Phage-Drug Conjugate
AssigneesThe University of Sydney, Westmead Institute For Medical Research, Western Sydney Local Health District
InventorsThi Thu Hien Duong, Jonathan Iredell, Huiping Huang
Life of this patent
Estimating the term…
Abstract
The present invention relates to phage-drug conjugates and methods for preparing phage-drug conjugates. The present invention also relates to methods of using the phage-drug conjugates.
Claims34
A conjugate of a phage linked with one or more types of active agent by a linker, wherein the phage is conjugated to the linker by one or more types of cleavable bond and the one or more types of active agent are each bound to the linker.
A method for preparing a conjugate of a phage linked with one or more types of active agent by a linker, the method comprising:
- providing a linker comprising one or more types of reactive functionality capable of forming a cleavable bond;
- binding one or more types of active agent to the linker;
- and
- conjugating a phage to the linker via at least one of the one or more types of reactive functionality;
- thereby providing the conjugate, wherein the phage is conjugated to the linker by one or more types of cleavable bond and the one or more types of active agent are each bound to the linker.
Dependencies are inferred from the claim text.