Devices and systems for automated assays and uses thereof

A magnetic module for reacting or labeling magnetic microcarriers, the module comprising:

• one or more well sets, each well set comprising:
• a reaction well;
• one or more reaction wash wells comprising a first reaction wash well and a last reaction wash well, each containing a reaction wash buffer, wherein the first reaction wash well and the last reaction wash well are the same well when there is only one reaction wash well in the well set;
• a labeling well containing labeling molecules in a labeling buffer;
• and
• one or more labeling wash wells comprising a first labeling wash well and a last labeling wash well, each containing a labeling wash buffer, wherein the first labeling wash well and the last labeling wash well are the same well when there is only one labeling wash well in the well set;
• one or more magnetic units, wherein each magnetic unit:
• is configured to move into, out of, and between each of the wells in a well set;
• is configured to attract the magnetic microcarriers and move the magnetic microcarriers into, out of, and between each of the wells in the well set;
• and
• comprises an upper end and a lower end;
• and
• one or more magnetic unit pockets, wherein each magnetic unit pocket:
• is positioned between each magnetic unit and a well set;
• is configured to move into, out of, and between each of the well in the well set;
• is configured to at least partially cover the lower end of each magnetic unit when the magnetic unit moves or slides into the magnetic unit pocket;
• and
• comprises an interior surface and an exterior surface,
• wherein the magnetic microcarriers are coupled to one or more capture agents, wherein the one or more capture agents can bind to one or more analytes.