Cannabinoid production in bacteria
AssigneeThe Regents of the University of California
InventorsTrevor N. Purdy, Bradley S. Moore
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Abstract
The disclosure relates to a method of making at least one cannabinoid comprising contacting at least one berberine bridge enzyme like (BBE-like) oxidase with at least one substrate, wherein the substrate comprises a cannabinoid precursor. The cannabinoid precursor can include cannabigerolic acid dihydrotetrachlorizine, prechlorizidine, cannabigerorcinic acid, grifolic acid, or a combination thereof.
Claims23
A method of making at least one cannabinoid comprising contacting at least one berberine bridge enzyme like (BBE-like) oxidase with at least one substrate, wherein the substrate comprises a cannabinoid precursor.
A host cell comprising an expression system comprising one or more expression cassettes, each expression cassette comprising a promotor operably linked to a nucleic acid segment encoding at least one berberine bridge enzyme like (BBE-like) oxidase.
Dependencies are inferred from the claim text.