US 2025/0027095 A1 · Target gene expression control system comprising dxCas9 and CRP derivative and preparation method therefor

Abstract

Disclosed are a plasmid comprising dxCas9 and a CRP derivative for controlling the expression of a target gene, a recombinant strain transformed with the plasmid, a preparation method therefor, a target gene control system, and a method for controlling the expression of a target gene, wherein the plasmid, recombinant strain, and expression control system according to the present invention can improve the production of high-value-added substances by construction of a system for simultaneously and multiply controlling the expression of target genes.

Claims20

Dependent claims

A plasmid for controlling the expression of a target gene, the plasmid comprising dxCas9 and a CRP derivative, wherein the CRP derivative is CRPAR1, CRPAR3, CRPAR23, or CRPAR123.

Dependencies are inferred from the claim text.

Facts

Application

18/776,896Filed 18 Jul 2024

Priority

KR 10-2023-009542921 Jul 2023

Published

23 Jan 2025

Term ends

Not estimatedThe source records don’t support an estimate.

Classification15 codes

C07K 14/4702
Not used: regulators; Modulating activity
C12N 15/70
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression: vectors or expression systems…
C07K 14/4737
Not used: c-reactive protein
C12N 1/20
Microorganisms; Compositions thereof ; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of…:…

Target gene expression control system comprising dxCas9 and CRP derivative and preparation method therefor

Life of this patent

Target gene expression control system comprising dxCas9 and CRP derivative and preparation method therefor

Life of this patent

Abstract

Claims20