Establishment of erythroid precursor cell line capable of conditional maturation using gene overexpression
AssigneeIucf-Hyu (Industry-University Cooperation Foundation Hanyang University)
InventorsEun Jung BAEK, Suyeon KIM, Kyeong Won JO, Ju Mi PARK
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Abstract
The present invention relates to the establishment of an immortalized erythroid precursor cell line capable of conditional maturation, and more specifically, the present invention provides an erythroid precursor cell for producing an erythrocyte having E6/E7 and Bcl-xL genes transduced therein, and a preparation method therefor.
Claims13
An erythroid progenitor cell transduced with a Bcl-xL gene and E6/E7 genes.
A method of producing an erythroid progenitor cell, comprising transducing a Bcl-xL gene and E6/E7 genes into an erythroid cell differentiated from a hematopoietic stem cell.
A recombinant vector comprising a Bcl-xL gene and E6/E7 genes.
Dependencies are inferred from the claim text.