US 2025/0025072 A1Published application

Device and method for measuring blood constituents

AssigneeSamsung Electronics Co., Ltd.

InventorsVladislav Valerievich LYCHAGOV, Anton Sergeevich MEDVEDEV, Elena Konstantinovna VOLKOVA, Gennady Dmitrievich MAMYKIN

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Abstract

A method for measuring blood constituents is provided. The method includes radiating an area of a subject's body, containing blood constituents and dynamic and static tissue components, with at least two light beams, detecting at least one backscattered light feedback from blood constituents and dynamic and static tissue components, the feedback representing at least one interferometric signal from each of the at least two light sources, filtering the at least one interferometric signals in accordance with a frequency band which contains frequencies of interferometric oscillations, defining dynamics of blood constituents, performing analog-to-digital (AD) conversion of the filtered signals at a frequency corresponding to the frequency band, to form discrete filtered signals, obtaining from the discrete filtered signals, a set of spectral-time features of signals, and obtaining concentration of the blood constituents based on functional relationships of the obtained set of spectral-time features of signals and concentrations of the blood constituents.

Claims20

Dependent claims

A method for measuring blood constituents by a device, the method comprising:

radiating an area of a subject's body, containing blood constituents and dynamic and static tissue components, with at least two light beams using at least two light sources;
detecting, using at least one photodetector, at least one backscattered light feedback from the blood constituents and dynamic and static tissue components, wherein the feedback represents at least one interferometric signal from each of the at least two light sources;
filtering, using a filter, the at least one interferometric signal in accordance with a signal frequency band which contains frequencies of interferometric oscillations;
performing analog-to-digital (AD) conversion of the filtered signals at a frequency corresponding to the signal frequency band of the filtered signal, to form discrete filtered signals;
obtaining, from the discrete filtered signals, a set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk), defining spectral and dynamic properties of the blood constituents,
where λ1, λ2, λ3, . . . , λn are wavelength indexes, and
where t1, . . . tk are time feature indexes, with spectral-time feature vλntk corresponding to time feature tk measured at wavelength λn;
and
obtaining a concentration of the blood constituents based on the obtained set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk) according to following expression:
c
1
≈
f
1
(
v
λ
1
t
1
,
v
λ
2
t
1
,
…
⁢
v
λ
n
t
1
,
…
⁢
v
λ
1
t
k
,
…
⁢
v
λ
n
t
k
)
⁢
c
2
≈
f
2
(
v
λ
1
t
1
,
v
λ
2
t
1
,
…
⁢
v
λ
n
t
1
,
…
⁢
v
λ
1
t
k
,
…
⁢
v
λ
n
t
k
)
⁢
…
⁢
c
m
≈
f
m
(
v
λ
1
t
1
,
v
λ
2
t
1
,
…
⁢
v
λ
n
t
1
,
…
⁢
v
λ
1
t
k
,
…
⁢
v
λ
n
t
k
)
where c1, c2, . . . ,cm are concentrations of the blood constituents, which are defined by respective set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk), and
where f1, f2, . . . , fm are functional relationships of the obtained set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk) and the concentrations of the blood constituents.

138 more elements

A device for measuring blood constituents, the device comprising:

at least two light sources;
at least one photodetector;
a filter;
an analog-to-digital (AD) converter;
memory storing one or more computer programs;
and
one or more processors communicatively coupled to the at least two light sources, the at least one photodetector, the filter, the AD converter, and the memory,
wherein the one or more computer programs include computer-executable instructions that, when executed by the one or more processors individually or collectively, cause the device to:
radiate an area of a subject's body, containing blood constituents and dynamic and static tissue components, with at least two light beams using at least two light sources;
detect, using the at least one photodetector, at least one backscattered light feedback from the blood constituents and dynamic and static tissue components, wherein the feedback represents at least one interferometric signal from each of the at least two light sources;
filter, using the filter, the at least one interferometric signal in accordance with a signal frequency band which contains frequencies of interferometric oscillations;
perform analog-to-digital (AD) conversion of the filtered signals at a frequency corresponding to the signal frequency band of the filtered signal, to form discrete filtered signals;
obtain, from the discrete filtered signals, a set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk), defining spectral and dynamic properties of the blood constituents,
where λ1, λ2, λ3, . . . , λn are wavelength indexes, and
where t1, . . . tk are time feature indexes, with spectral-time feature vλntk corresponding to time feature tk measured at wavelength λn;
and
obtain a concentration of the blood constituents based on the obtained set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk) according to following expression:
c
1
≈
f
1
(
v
λ
1
t
1
,
v
λ
2
t
1
,
…
⁢
v
λ
n
t
1
,
…
⁢
v
λ
1
t
k
,
…
⁢
v
λ
n
t
k
)
⁢
c
2
≈
f
2
(
v
λ
1
t
1
,
v
λ
2
t
1
,
…
⁢
v
λ
n
t
1
,
…
⁢
v
λ
1
t
k
,
…
⁢
v
λ
n
t
k
)
⁢
…
⁢
c
m
≈
f
m
(
v
λ
1
t
1
,
v
λ
2
t
1
,
…
⁢
v
λ
n
t
1
,
…
⁢
v
λ
1
t
k
,
…
⁢
v
λ
n
t
k
)
where c1, c2, . . . ,cm are concentrations of the blood constituents, which are defined by respective set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk), and
where f1, f2, . . . , fm are functional relationships of the obtained set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk) and the concentrations of the blood constituents.

146 more elements

One or more non-transitory computer-readable storage media storing one or more computer programs including computer-executable instructions that, when executed by one or more processors of an electronic device individually or collectively, cause the electronic device to perform operations, the operations comprising:

radiating an area of a subject's body, containing blood constituents and dynamic and static tissue components, with at least two light beams using at least two light sources;
detecting, using at least one photodetector, at least one backscattered light feedback from the blood constituents and dynamic and static tissue components, wherein the feedback represents at least one interferometric signal from each of the at least two light sources;
filtering, using a filter, the at least one interferometric signal in accordance with a signal frequency band which contains frequencies of interferometric oscillations;
performing analog-to-digital (AD) conversion of the filtered signals at a frequency corresponding to the signal frequency band of the filtered signal, to form discrete filtered signals;
obtaining, from the discrete filtered signals, a set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk), defining spectral and dynamic properties of the blood constituents,
where λ1, λ2, λ3, . . . , λn are wavelength indexes, and
where t1, . . . tk are time feature indexes, with spectral-time feature vλntk corresponding to time feature tk measured at wavelength λn;
and
obtaining a concentration of the blood constituents based on the obtained set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk) according to following expression:
c
1
≈
f
1
(
v
λ
1
t
1
,
v
λ
2
t
1
,
…
⁢
v
λ
n
t
1
,
…
⁢
v
λ
1
t
k
,
…
⁢
v
λ
n
t
k
)
⁢
c
2
≈
f
2
(
v
λ
1
t
1
,
v
λ
2
t
1
,
…
⁢
v
λ
n
t
1
,
…
⁢
v
λ
1
t
k
,
…
⁢
v
λ
n
t
k
)
⁢
…
⁢
c
m
≈
f
m
(
v
λ
1
t
1
,
v
λ
2
t
1
,
…
⁢
v
λ
n
t
1
,
…
⁢
v
λ
1
t
k
,
…
⁢
v
λ
n
t
k
)
where c1, c2, . . . ,cm are concentrations of the blood constituents, which are defined by respective set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk), and where f1, f2, . . . , fm are functional relationships of the obtained set of spectral-time features (vλ1t1, vλ2t1, . . . vλt1, . . . vλ1tk, . . . vλntk) and the concentrations of the blood constituents.

137 more elements

Dependencies are inferred from the claim text.

Facts

Application: 18/909,345Filed 8 Oct 2024
Priority: RU 202211345119 May 2022
Published: 23 Jan 2025
Term ends: Not estimatedThe source records don’t support an estimate.

Classification8 codes

A61B 5/1455
Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g.…: using…
A61B 5/6802
Specially adapted to be attached to or worn on the body surface: sensor mounted on worn items
A61B 5/7225
Signal processing specially adapted for physiological signals or for diagnostic purposes: details of analogue processing, e.g. isolation…
G16H 10/40
ICT specially adapted for the handling or processing of patient-related medical or healthcare data: for data related to laboratory analysis, e.g.…

Family

Application18/909,345Continuation
US 2025/0025072 A1This patent

From the US filing history. Foreign family members aren’t listed.

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