Systems and methods for medical imaging

An imaging device comprising:

• a housing;
• an insertion portion of housing, the insertion portion of the housing having an elongated optical axis, wherein a first optical signal and a second optical signal are transmitted along the elongated optical axis, wherein the first optical signal and the second optical signal each comprise a distinct wavelength range, wherein the insertion portion comprises an even number of pairs of lenses and an unpaired lens;
• a beam splitter positioned distal to the insertion portion configured to deliver the first optical signal to a first imaging unit and configured to deliver the second optical signal to a second imaging unit;
• a lens along a first imaging axis distal to the beam splitter, wherein an image distal to the lens on the first imaging portion is inverted;
• and a pair of lenses and an unpaired lens on a second imaging axis distal to the beam splitter, wherein an image distal to the unpaired lens on the second imaging axis is right-side-up.

An imaging device comprising:

• a housing;
• an insertion portion of the housing, the insertion portion having an elongated optical axis, wherein a first optical signal and a second optical signal are transmitted along the elongated optical axis, wherein the first optical signal and the second optical signal each have a distinct wavelength range;
• a beam splitter configured to deliver the first optical signal to a first imaging unit and configured to deliver the second optical signal to a second imaging unit;
• one or more markers along the elongated optical axis;
• and
• a focusing lens on an optical path of either the first imaging unit or the second imaging unit, wherein adjustment of the focusing lens is configured to bring an image of the one or more markers into focus on both of the first imaging unit and the second imaging unit.

A system comprising:

• a housing;
• an insertion portion of the housing, the insertion portion having an elongated optical axis, wherein a first optical signal and a second optical signal are transmitted along the elongated optical axis, wherein the first optical signal and the second optical signal each have a distinct wavelength range;
• a beam splitter configured to deliver the first optical signal to a first imaging unit and configured to deliver the second optical signal to a second imaging unit, wherein the second imaging unit is releasably attached to the system;
• one or more markers along the elongated optical axis;
• and
• a focusing lens on an optical path of either the first imaging unit or the second imaging unit, wherein adjustment of the lens is configured to bring an image of the one or more markers into focus on both of the first imaging unit and the second imaging unit.

A system comprising:

• a housing;
• an insertion portion of the housing, the insertion portion having an elongated optical axis, wherein a first optical signal and a second optical signal are transmitted along the elongated optical axis, wherein the first optical signal and the second optical signal each have a distinct wavelength range;
• a beam splitter configured to deliver the first optical signal to a first imaging unit and configured to deliver the second optical signal to a second imaging unit, wherein the second imaging unit is releasably attached to the system;
• first and second sets of fiducial marks along the elongated optical axis, wherein the first set of fiducial marks has finer or narrower notches as compared to the second set of fiducial marks, and wherein differences in resolution of the notches between the first set of fiducial marks and the second set of fiducial marks are used to determine an adjustment needed to focus;
• a lens on an optical path of either the first imaging unit or the second imaging unit, wherein the optical path is rotatable relative to the first imaging unit, wherein the lens is adjustable to bring an image of the one or more sets of fiducial marks into focus on both of the first imaging unit and the second imaging unit;
• and
• an image processor operatively coupled to the first imaging unit, the second imaging units or both and configured to determine the adjustment needed to focus based on the differences in resolution of the notches of the fiducial marks.

A method of imaging a target site, the method comprising:

• receiving a first optical signal and a second optical signal from the target site wherein the first optical signal and the second optical signal each comprise a distinct wavelength range;
• directing the first optical signal to a first imaging unit, wherein the first imaging unit is integrated within a housing of a laparoscope or an endoscope;
• coupling a second imaging unit to the laparoscope or the endoscope;
• and directing the second optical signal to the second imaging unit.