Bioactive peptides and methods of use thereof
AssigneeOp-T LLC
InventorsDavid H. Wagner, JR., Gisela M. Vaitaitis, Charles W. Henry, Martin Glenn Yussman
Life of this patent
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Abstract
Methods and compositions are disclosed for treating and preventing cytokine release syndrome (CRS). acute respiratory distress syndrome (CRS), and alveolar capillary injury (ACI) in a subject.
Claims15
-50. (canceled)
A method of treating cytokine release syndrome (CRS), the method comprising administering to a subject having CRS an effective amount of a peptide that alters or modulates the binding or interaction between CD40 complex and CD 154 proteins, wherein the peptide comprises SEQ ID NO:
- 4.
A method of treating acute respiratory distress syndrome (ARDS), the method comprising administering to a subject having ARDS an effective amount of a peptide that alters or modulates the binding or interaction between CD40 complex and CD 154 proteins, wherein the peptide comprises SEQ ID NO:
- 4.
A method of treating acute lung injury (ALI), the method comprising administering to a subject having ALI an effective amount of a peptide that alters or modulates the binding or interaction between CD40 complex and CD 154 proteins, wherein the peptide comprises SEQ ID NO:
- 4.
Dependencies are inferred from the claim text.