Cell-potent bisubstrate inhibitors for nicotinamide n-methyltransferase (nnmt) and uses thereof

A compound having the formula (I):

• or a pharmaceutically acceptable salt thereof, wherein,
• R1 is an alkyl, a haloalkyl, an alkenyl, an alkynyl, an aminoalkanoic acid, an acyl, an arylalkylacyl, an arylacyl, a cycloalkyl, a heterocyclyl, an aryl, a heteroaryl, an arylalkyl, or a heteroarylalkyl;
• R2, R3, R4, and R5 are, independently, hydrogen, a halo, a haloalkyl, an alkyl, an amino, an alkylamino, or an alkylaminoalkyl;
• and
• R6, R7, and R8 are, independently, hydrogen, methyl, hydroxyl, methoxyl, trifluoromethyl, or a halo;
• and
• R9 is an amine or methyl.